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  • General Conditions - Canadian Hemophilia Society
    a survivor HCV treatment support for 1986 1990 claimants National Endowment Fund Scholarship University of Ottawa Criminalization of HIV Non Disclosure HIV Know your rights US travel ban lifted World Hepatitis Day Recommendations for a Canadian Hepatitis C Strategy 2005 Hepatitis C An information booklet Alternative therapies Diagnosis Final Thoughts Getting treatment Healthy Lifestyle Hepatitis C Introduction Hepatitis C and HIV Co infection Psychosocial Aspects Standards of Care Symptoms Treatment Options for Hepatitis C Liver transplantation Youth Web About Us News Feed To Contact Us Commemoration of the Tainted Blood Tragedy Tree of Life Commemorations Canadian Blood Services November 26 2007 Héma Québec October 9 2008 CHS Newfounland Labrador Chapter Commemoration 2008 2009 Hemophilia Saskatchewan Commemoration 2009 CHS British Columbia Chapter Commemoration 2009 CHS Prince Edward Island Chapter Commemoration 2009 Hemophilia Ontario Commemoration 2009 Hemophilia Ontario Commemoration 2010 CHS Manitoba Chapter Commemoration 2010 Hemophilia Ontario Commemoration 2011 New Brunswick Chapter Commemoration 2012 Hemophilia Ontario Commemoration 2012 Hemophilia Saskatchewan Commemoration 2012 Hemophilia Saskatchewan Commemoration 2103 Hemophilia Ontario Commemoration 2013 Hemophilia Alberta Commemoration 2014 Media Room Press releases 2009 2011 Press releases 2006 2008 Search Français Our Partners General Conditions 1 General Conditions 2 Additional Grant Conditions and Grantee Obligations 3 Ethical Considerations 1 General Conditions 1 1 Application Forms The Application Form may be obtained by clicking on the following link Application Form Applications forms must be completed and submitted electronically to the Canadian Hemophilia Society chs hemophilia ca and one 1 original paper copy including signatures must be sent to the National Office of the Canadian Hemophilia Society 666 Sherbrooke Street West Suite 301 Montreal QC H3A 1E7 1 2 Application Deadline Completed application forms and supporting documents must arrive at the National Office of the Canadian Hemophilia Society by November 14 2014 If the CHS receives the application after the deadline date but it is postmarked on or before the deadline date then it is considered to have been submitted on time The names of the successful applicants will be announced by March 2015 First time applicants are encouraged to seek advice from experienced investigators in the preparation of their applications Please note that the Research Proposal Item 16 of the application must not exceed 5000 words excluding figures and references Supporting materials should include only previously published articles or materials accepted for publication 1 3 Grant Year and Amount Individual grants valued at 75 000 per year and per project will be awarded to researchers for a maximum of 150 000 which can be expended over 2 or 3 years If a two year award is provided the second year of funding is dependent on evidence of progress as described in the required progress report Grant funding will begin on April 1 of each year 1 4 Grant Payments Yearly grants will normally be disbursed in two payments in each year and sent to the financial officer of the host institution 1 5 Research Summaries The Canadian Hemophilia Society CHS requires within the application form a 200 word typewritten lay description of the research to be undertaken in non scientific Grade 12 readability for inclusion in the Society s publications should the proposal be accepted 1 6 Notification of Grants Following funding decisions successful applicants will be sent official notification informing them of the type duration and amount of their grant A copy of the notification is sent to the accountant at the institution concerned The award must be acknowledged by returning an acceptance note within 15 days of the CHS notification otherwise the award will be withdrawn Unsuccessful applicants are also advised at the conclusion of the project application review process 1 7 Appeals The Research Peer Review Committee of the Canadian Hemophilia Society will make recommendations on the awarding of the grants and the final decision will be made by the CHS Board of Directors No appeals will be considered 2 Additional Grant Conditions and Grantee Obligations 2 1 Statement of Expenditures A statement of all expenditures for the grant signed by the candidate and the financial officer of each institution must be received at the CHS s offices within 2 months of the end date of the grant term An institution finance expenditure report is acceptable to avoid duplication of effort by the researcher Failure to fulfill this requirement may lead to exclusion from future research grant competitions If delay is anticipated the CHS must be informed 2 2 Changes in the Use of the Grant The use of funds for purposes other than stated in the application must be approved in advance by the CHS 2 3 Unexpended Balances The Canadian Hemophilia Society does not permit carrying forward into the next grant year an unexpected balance in excess of 5 000 Prior written request to the CHS is required to carry forward a balance that exceeds 5 000 2 4 Termination of the Grant Upon termination of the project any unexpended balance of funds must be returned to the CHS 2 5 Travel Expenses A grantee may use 1 500 annually from the award for the purpose of travel in connection with the grant and if needed an additional amount representing one percent 1 of the annual value of the award 2 6 Title to Equipment Title to any equipment obtained with the Canadian Hemophilia Society s funds shall be held by the host institution on the condition that for a 12 month period following termination of grant the CHS may transfer title to another institution Prior written authorization for the transfer of funds or equipment by a grantee to another institution must be obtained from the CHS 2 7 Interim Final Report Abstract Requirements Research grant recipients are required to provide a project progress report for each year of funding allocation This report will serve as the basis for review of the project and approval of second year funding where applicable The progress report will also provide supporting rationale if required for approval of project modifications and or extension requests Within 2 months

    Original URL path: http://www.hemophilia.ca/en/research/chs-dream-of-a-cure-research-program/general-conditions/ (2014-10-09)
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  • Application Forms - Canadian Hemophilia Society
    Centres To Support Us To Volunteer To Contact Us Bleeding Disorders Hemophilia A and B What is hemophilia The history of hemophilia The clotting problem in hemophilia Heredity of hemophilia The symptoms of hemophilia The diagnosis of hemophilia The treatment of hemophilia Comprehensive hemophilia care Factor replacement therapy Other treatments The complications of hemophilia Blood borne infections Inhibitors Joint damage Precautions Carriers of hemophilia A and B Von Willebrand disease Preface Acknowledgements An Introduction to von Willebrand disease Types of von Willebrand disease Heredity of von Willebrand disease Symptoms of von Willebrand disease Diagnosis of von Willebrand disease Treatment options for von Willebrand disease Introduction Recommended Treatments for Men and Women Not Recommended Treatments Recommended Treatments for Women with Gynecological Complications Living with von Willebrand disease Comprehensive care Safety of Blood Products Nose bleeds Conception Pregnancy and Childbirth Medication to Be Avoided Exercise Fitness and Sports Child Care and Schooling Employment Insurance Travelling Medical Identification Final word Where to get more information Hemophilia Bleeding Disorder Treatment Centres Glossary Bibliography Other factor deficiencies Factor I deficiency Fibrinogen deficiency Factor II deficiency Prothrombin deficiency Factor V deficiency Combined factor V and factor VIII deficiency Factor VII deficiency Factor X deficiency Factor XI deficiency Hemophilia C Factor XII deficiency Factor XIII deficiency Summary Chart Platelet function disorders Introduction Symptoms of platelet function disorders Diagnosis of platelet function disorders Types of platelet function disorders Treatment of platelet function disorders Precautions PDF documents Clotting factor concentrates Women Inherited bleeding disorders affecting women Symptoms Diagnosis Inheritance Medical treatment options for menorrhagia and other symptoms Gynaecological treatment options for menorrhagia Precautions for pregnant women Staying healthy Bleeding disorder treatment centres Educational resources Stories from women and girls who bleed too much About the CHS Support and Education Passport to well being Destination fitness Home care The road to independence Roadmap for managing pain Navigating the emergency department Bon Voyage Travelling with a bleeding disorder Charting Your Course PEP Parents Empowering Parents program Vocational assessment tool Career planning and scholarship links Scholarship Program Federal and Provincial Support Programs Insurance coverage Educational Material Printed documents Bleeding disorders in women Carriers of hemophilia A or B Hemophilia Hepatitis C HIV Inhibitors Physical activity and sports Platelet function disorders Rare factor deficiencies Relevant to all bleeding disorders Resources for children Von Willebrand disease Videos Care and Treatment Emergency Care Pain Management Nursing Physiotherapy Introduction Constitution of the Canadian Physiotherapists in Hemophilia Care CPHC Standards of Physiotherapy Care and Assessment Selected Journal Articles Educational material Bibliography Other resources Social Work Community Partners and Links Practice Guidelines Mission Services Interventions Standards of Practice Comprehensive Care Standards Safe Secure Blood Supply Products in the pipeline CHS Policy on Paid Plasma Donations Report Cards on Canada s Blood System 2008 2010 Report Card on Canada s Blood System 2005 2007 Report Card on Canada s Blood System 2003 2004 Report Card on Canada s Blood System 2002 Report Card on Canada s Blood System 1999 Report Card on Canada s Blood System Inhibitor rates related

    Original URL path: http://www.hemophilia.ca/en/research/chs-dream-of-a-cure-research-program/application-forms/ (2014-10-09)
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  • Summer Studentships in Inherited Bleeding Disorders Research - Canadian Hemophilia Society
    girls who bleed too much About the CHS Support and Education Passport to well being Destination fitness Home care The road to independence Roadmap for managing pain Navigating the emergency department Bon Voyage Travelling with a bleeding disorder Charting Your Course PEP Parents Empowering Parents program Vocational assessment tool Career planning and scholarship links Scholarship Program Federal and Provincial Support Programs Insurance coverage Educational Material Printed documents Bleeding disorders in women Carriers of hemophilia A or B Hemophilia Hepatitis C HIV Inhibitors Physical activity and sports Platelet function disorders Rare factor deficiencies Relevant to all bleeding disorders Resources for children Von Willebrand disease Videos Care and Treatment Emergency Care Pain Management Nursing Physiotherapy Introduction Constitution of the Canadian Physiotherapists in Hemophilia Care CPHC Standards of Physiotherapy Care and Assessment Selected Journal Articles Educational material Bibliography Other resources Social Work Community Partners and Links Practice Guidelines Mission Services Interventions Standards of Practice Comprehensive Care Standards Safe Secure Blood Supply Products in the pipeline CHS Policy on Paid Plasma Donations Report Cards on Canada s Blood System 2008 2010 Report Card on Canada s Blood System 2005 2007 Report Card on Canada s Blood System 2003 2004 Report Card on Canada s Blood System 2002 Report Card on Canada s Blood System 1999 Report Card on Canada s Blood System Inhibitor rates related to treatment product in previously untreated patients Statement from the WFH variant Creutzfeldt Jakob disease vCJD CHS position on donor deferrals CHS position on HIV O deferral in Africa Hemophilia Research Million Dollar Club Research CHS Dream of a Cure Research Program General Criteria General Conditions Application Forms Summer Studentships in Inherited Bleeding Disorders Research CHS Research Grants for 2014 CHS Research Grants for 2013 CHS Research Grants for 2012 CHS Research Grants for 2011 CHS Research Grants for 2010 CHS Research Grants for 2009 CHS Research Grants for 2008 CHS Research Grants for 2007 CHS Research Grants for 2006 CHS Research Grants for 2005 The CHS Pfizer Care Until Cure Research Program General Criteria General Conditions Application Form Research Projects Funded in 2014 Research Projects Funded in 2013 Research Projects Funded in 2012 Research Projects Funded in 2011 Research Projects Funded in 2010 Research Projects Funded in 2009 Research Projects Funded in 2008 Research Projects Funded in 2007 Research Projects Funded in 2006 Research Projects Funded in 2005 CHS Novo Nordisk Psychosocial Research Program General Criteria General Conditions Application form Research Project Funded in 2014 Hemostasis Fellowship Program General Criteria General Conditions Application form Research Project Funded in 2014 Research Project Funded in 2013 Research Project Funded in 2012 Research Project Funded in 2011 Research Project Funded in 2010 Research Project Funded in 2009 Research Project Funded in 2008 Research Project Funded in 2007 Research Project Funded in 2006 Research Project Funded in 2005 CHS Baxter Fellowship Program General Criteria General Conditions Application Form Research Projects Funded in 2014 Research Project Funded in 2013 Opportunities to participate in research Opportunities to participate in marketing research studies International Development

    Original URL path: http://www.hemophilia.ca/en/research/chs-dream-of-a-cure-research-program/summer-studentships-in-inherited-bleeding-disorders-research/ (2014-10-09)
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  • CHS Research Grants for 2014 - Canadian Hemophilia Society
    CHS position on HIV O deferral in Africa Hemophilia Research Million Dollar Club Research CHS Dream of a Cure Research Program General Criteria General Conditions Application Forms Summer Studentships in Inherited Bleeding Disorders Research CHS Research Grants for 2014 CHS Research Grants for 2013 CHS Research Grants for 2012 CHS Research Grants for 2011 CHS Research Grants for 2010 CHS Research Grants for 2009 CHS Research Grants for 2008 CHS Research Grants for 2007 CHS Research Grants for 2006 CHS Research Grants for 2005 The CHS Pfizer Care Until Cure Research Program General Criteria General Conditions Application Form Research Projects Funded in 2014 Research Projects Funded in 2013 Research Projects Funded in 2012 Research Projects Funded in 2011 Research Projects Funded in 2010 Research Projects Funded in 2009 Research Projects Funded in 2008 Research Projects Funded in 2007 Research Projects Funded in 2006 Research Projects Funded in 2005 CHS Novo Nordisk Psychosocial Research Program General Criteria General Conditions Application form Research Project Funded in 2014 Hemostasis Fellowship Program General Criteria General Conditions Application form Research Project Funded in 2014 Research Project Funded in 2013 Research Project Funded in 2012 Research Project Funded in 2011 Research Project Funded in 2010 Research Project Funded in 2009 Research Project Funded in 2008 Research Project Funded in 2007 Research Project Funded in 2006 Research Project Funded in 2005 CHS Baxter Fellowship Program General Criteria General Conditions Application Form Research Projects Funded in 2014 Research Project Funded in 2013 Opportunities to participate in research Opportunities to participate in marketing research studies International Development Karttik Shah Youth Fellowship International Twinning Projects Canadian Centre Twins Hemophilia Treatment Centre partnerships ended recently Canadian Hemophilia Society International Projects Fund Canadian Organizational Twins Recently closed twinning partnerships Treatment Centres British Columbia Alberta Saskatchewan Manitoba Ontario Quebec New Brunswick Prince Edward Island Nova Scotia Newfoundland and Labrador HCV HIV Hepatitis C and HIV Compensation I am a survivor HCV treatment support for 1986 1990 claimants National Endowment Fund Scholarship University of Ottawa Criminalization of HIV Non Disclosure HIV Know your rights US travel ban lifted World Hepatitis Day Recommendations for a Canadian Hepatitis C Strategy 2005 Hepatitis C An information booklet Alternative therapies Diagnosis Final Thoughts Getting treatment Healthy Lifestyle Hepatitis C Introduction Hepatitis C and HIV Co infection Psychosocial Aspects Standards of Care Symptoms Treatment Options for Hepatitis C Liver transplantation Youth Web About Us News Feed To Contact Us Commemoration of the Tainted Blood Tragedy Tree of Life Commemorations Canadian Blood Services November 26 2007 Héma Québec October 9 2008 CHS Newfounland Labrador Chapter Commemoration 2008 2009 Hemophilia Saskatchewan Commemoration 2009 CHS British Columbia Chapter Commemoration 2009 CHS Prince Edward Island Chapter Commemoration 2009 Hemophilia Ontario Commemoration 2009 Hemophilia Ontario Commemoration 2010 CHS Manitoba Chapter Commemoration 2010 Hemophilia Ontario Commemoration 2011 New Brunswick Chapter Commemoration 2012 Hemophilia Ontario Commemoration 2012 Hemophilia Saskatchewan Commemoration 2012 Hemophilia Saskatchewan Commemoration 2103 Hemophilia Ontario Commemoration 2013 Hemophilia Alberta Commemoration 2014 Media Room Press releases 2009 2011 Press releases 2006 2008 Search Français Our

    Original URL path: http://www.hemophilia.ca/en/research/chs-dream-of-a-cure-research-program/chs-research-grants-for-2014/ (2014-10-09)
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  • CHS Research Grants for 2013 - Canadian Hemophilia Society
    on HIV O deferral in Africa Hemophilia Research Million Dollar Club Research CHS Dream of a Cure Research Program General Criteria General Conditions Application Forms Summer Studentships in Inherited Bleeding Disorders Research CHS Research Grants for 2014 CHS Research Grants for 2013 CHS Research Grants for 2012 CHS Research Grants for 2011 CHS Research Grants for 2010 CHS Research Grants for 2009 CHS Research Grants for 2008 CHS Research Grants for 2007 CHS Research Grants for 2006 CHS Research Grants for 2005 The CHS Pfizer Care Until Cure Research Program General Criteria General Conditions Application Form Research Projects Funded in 2014 Research Projects Funded in 2013 Research Projects Funded in 2012 Research Projects Funded in 2011 Research Projects Funded in 2010 Research Projects Funded in 2009 Research Projects Funded in 2008 Research Projects Funded in 2007 Research Projects Funded in 2006 Research Projects Funded in 2005 CHS Novo Nordisk Psychosocial Research Program General Criteria General Conditions Application form Research Project Funded in 2014 Hemostasis Fellowship Program General Criteria General Conditions Application form Research Project Funded in 2014 Research Project Funded in 2013 Research Project Funded in 2012 Research Project Funded in 2011 Research Project Funded in 2010 Research Project Funded in 2009 Research Project Funded in 2008 Research Project Funded in 2007 Research Project Funded in 2006 Research Project Funded in 2005 CHS Baxter Fellowship Program General Criteria General Conditions Application Form Research Projects Funded in 2014 Research Project Funded in 2013 Opportunities to participate in research Opportunities to participate in marketing research studies International Development Karttik Shah Youth Fellowship International Twinning Projects Canadian Centre Twins Hemophilia Treatment Centre partnerships ended recently Canadian Hemophilia Society International Projects Fund Canadian Organizational Twins Recently closed twinning partnerships Treatment Centres British Columbia Alberta Saskatchewan Manitoba Ontario Quebec New Brunswick Prince Edward Island Nova Scotia Newfoundland and Labrador HCV HIV Hepatitis C and HIV Compensation I am a survivor HCV treatment support for 1986 1990 claimants National Endowment Fund Scholarship University of Ottawa Criminalization of HIV Non Disclosure HIV Know your rights US travel ban lifted World Hepatitis Day Recommendations for a Canadian Hepatitis C Strategy 2005 Hepatitis C An information booklet Alternative therapies Diagnosis Final Thoughts Getting treatment Healthy Lifestyle Hepatitis C Introduction Hepatitis C and HIV Co infection Psychosocial Aspects Standards of Care Symptoms Treatment Options for Hepatitis C Liver transplantation Youth Web About Us News Feed To Contact Us Commemoration of the Tainted Blood Tragedy Tree of Life Commemorations Canadian Blood Services November 26 2007 Héma Québec October 9 2008 CHS Newfounland Labrador Chapter Commemoration 2008 2009 Hemophilia Saskatchewan Commemoration 2009 CHS British Columbia Chapter Commemoration 2009 CHS Prince Edward Island Chapter Commemoration 2009 Hemophilia Ontario Commemoration 2009 Hemophilia Ontario Commemoration 2010 CHS Manitoba Chapter Commemoration 2010 Hemophilia Ontario Commemoration 2011 New Brunswick Chapter Commemoration 2012 Hemophilia Ontario Commemoration 2012 Hemophilia Saskatchewan Commemoration 2012 Hemophilia Saskatchewan Commemoration 2103 Hemophilia Ontario Commemoration 2013 Hemophilia Alberta Commemoration 2014 Media Room Press releases 2009 2011 Press releases 2006 2008 Search Français Our Partners CHS Research Grants for 2013 Incorporation of rFVIII into platelets as a potential therapy in patients with inhibitory antibodies to factor VIII Novel imaging techniques for assessment of early cartilage and soft tissue changes in haemophilic ankles Oral administration of FVIII DNA to modulate inhibitors in hemophilia mice Platelet type von Willebrand disease Novel studies in the PT VWD mouse model The effect of FVIII on complement system activation In vitro clotting assays measuring equivalent concentration of FEIBA and rFVIIa Investigating the Influence of SNPs Single Nucleotide Polymorphisms on variability of the Type 2B VWD phenotype Incorporation of rFVIII into platelets as a potential therapy in patients with inhibitory antibodies to factor VIII Dr Walter Kahr The Hospital for Sick Children Toronto Ontario First year funding Current treatment of severe hemophilia A patients in Canada involves regular injections of recombinant factor VIII rFVIII This treatment is effective but rFVIII injections are usually frequent because factor does not stay long in the blood stream and around 25 of patients develop inhibitors that block rFVIII effectiveness Work is underway to develop longer lasting forms of rFVIII and limit the effects of inhibitors One approach involves platelets the tiny abundant blood cells that coordinate blood clotting Platelets normally do not contain FVIII but genetic engineering has been used to make mouse platelets containing FVIII that have proven to be effective in preventing bleeding in hemophilic mice even when they have inhibitors We have been working on ways to load platelets with rFVIII that do not involve the risk expense and uncertainties of genetic engineering Our preliminary work shows that this is possible and that rFVIII loaded platelets can inhibit bleeding in hemophilic mice The goal of our proposed project is to improve our methods for making rFVIII loaded platelets and to demonstrate their potential for use in hemophilia patients with inhibitors who are often difficult to treat with conventional therapies Novel imaging techniques for assessment of early cartilage and soft tissue changes in haemophilic ankles Dr Andrea Doria The Hospital for Sick Children Toronto Ontario Second year funding continued in 2013 due to late start Co investigators Dr Aaron Fenster Dr Marshall Sussman Dr Victor Blanchette RATIONALE AND BACKGROUND Hemophilia is an inherited bleeding disorder characterized by the lack of coagulation factors which results in an inability to control bleeding into joints leading to long term joint damage Prophylaxis reduces the joint symptoms and avoids further degeneration of the joints however it should be started prior to the development of cartilage lesions Repeated extravazation of blood into the joint cavity is the factor responsible for cartilage degeneration in hemophilic arthropathy Microstructural cartilage changes are thought to precede macroscopic cartilage lesions 8 which are responsible for most of the morbidity of hemophilic arthropathy Conventional imaging techniques are unable to visualize early soft tissue and cartilage changes Evaluation of soft tissue changes and microstructural cartilage changes with sensitive imaging tools may direct clinical management and prophylaxis towards avoiding further irreversible macroscopic osteochondral damage New functional MRI

    Original URL path: http://www.hemophilia.ca/en/research/chs-dream-of-a-cure-research-program/chs-research-grants-for-2013/ (2014-10-09)
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  • CHS Research Grants for 2012 - Canadian Hemophilia Society
    Canada s Blood System 2002 Report Card on Canada s Blood System 1999 Report Card on Canada s Blood System Inhibitor rates related to treatment product in previously untreated patients Statement from the WFH variant Creutzfeldt Jakob disease vCJD CHS position on donor deferrals CHS position on HIV O deferral in Africa Hemophilia Research Million Dollar Club Research CHS Dream of a Cure Research Program General Criteria General Conditions Application Forms Summer Studentships in Inherited Bleeding Disorders Research CHS Research Grants for 2014 CHS Research Grants for 2013 CHS Research Grants for 2012 CHS Research Grants for 2011 CHS Research Grants for 2010 CHS Research Grants for 2009 CHS Research Grants for 2008 CHS Research Grants for 2007 CHS Research Grants for 2006 CHS Research Grants for 2005 The CHS Pfizer Care Until Cure Research Program General Criteria General Conditions Application Form Research Projects Funded in 2014 Research Projects Funded in 2013 Research Projects Funded in 2012 Research Projects Funded in 2011 Research Projects Funded in 2010 Research Projects Funded in 2009 Research Projects Funded in 2008 Research Projects Funded in 2007 Research Projects Funded in 2006 Research Projects Funded in 2005 CHS Novo Nordisk Psychosocial Research Program General Criteria General Conditions Application form Research Project Funded in 2014 Hemostasis Fellowship Program General Criteria General Conditions Application form Research Project Funded in 2014 Research Project Funded in 2013 Research Project Funded in 2012 Research Project Funded in 2011 Research Project Funded in 2010 Research Project Funded in 2009 Research Project Funded in 2008 Research Project Funded in 2007 Research Project Funded in 2006 Research Project Funded in 2005 CHS Baxter Fellowship Program General Criteria General Conditions Application Form Research Projects Funded in 2014 Research Project Funded in 2013 Opportunities to participate in research Opportunities to participate in marketing research studies International Development Karttik Shah Youth Fellowship International Twinning Projects Canadian Centre Twins Hemophilia Treatment Centre partnerships ended recently Canadian Hemophilia Society International Projects Fund Canadian Organizational Twins Recently closed twinning partnerships Treatment Centres British Columbia Alberta Saskatchewan Manitoba Ontario Quebec New Brunswick Prince Edward Island Nova Scotia Newfoundland and Labrador HCV HIV Hepatitis C and HIV Compensation I am a survivor HCV treatment support for 1986 1990 claimants National Endowment Fund Scholarship University of Ottawa Criminalization of HIV Non Disclosure HIV Know your rights US travel ban lifted World Hepatitis Day Recommendations for a Canadian Hepatitis C Strategy 2005 Hepatitis C An information booklet Alternative therapies Diagnosis Final Thoughts Getting treatment Healthy Lifestyle Hepatitis C Introduction Hepatitis C and HIV Co infection Psychosocial Aspects Standards of Care Symptoms Treatment Options for Hepatitis C Liver transplantation Youth Web About Us News Feed To Contact Us Commemoration of the Tainted Blood Tragedy Tree of Life Commemorations Canadian Blood Services November 26 2007 Héma Québec October 9 2008 CHS Newfounland Labrador Chapter Commemoration 2008 2009 Hemophilia Saskatchewan Commemoration 2009 CHS British Columbia Chapter Commemoration 2009 CHS Prince Edward Island Chapter Commemoration 2009 Hemophilia Ontario Commemoration 2009 Hemophilia Ontario Commemoration 2010 CHS Manitoba Chapter Commemoration 2010 Hemophilia Ontario Commemoration 2011 New Brunswick Chapter Commemoration 2012 Hemophilia Ontario Commemoration 2012 Hemophilia Saskatchewan Commemoration 2012 Hemophilia Saskatchewan Commemoration 2103 Hemophilia Ontario Commemoration 2013 Hemophilia Alberta Commemoration 2014 Media Room Press releases 2009 2011 Press releases 2006 2008 Search Français Our Partners CHS Research Grants for 2012 Novel imaging techniques for assessment of early cartilage and soft tissue changes in haemophilic ankles Oral administration of FVIII DNA to modulate inhibitors in hemophilia mice Platelet type von Willebrand disease Novel studies in the PT VWD mouse model Effects of anticoagulants on clot formation in factor VIII deficient plasma Determinants of health related quality of life among patients with von Willebrand disease Treatment adherence on the Canadian Hemophilia Prophylaxis Study Factor XIII deficiency in Canada Novel imaging techniques for assessment of early cartilage and soft tissue changes in haemophilic ankles Dr Andrea Doria The Hospital for Sick Children Toronto Ontario First year funding continued in 2012 due to late start Co investigators Dr Aaron Fenster Dr Marshall Sussman Dr Victor Blanchette RATIONALE AND BACKGROUND Hemophilia is an inherited bleeding disorder characterized by the lack of coagulation factors which results in an inability to control bleeding into joints leading to long term joint damage Prophylaxis reduces the joint symptoms and avoids further degeneration of the joints however it should be started prior to the development of cartilage lesions Repeated extravazation of blood into the joint cavity is the factor responsible for cartilage degeneration in hemophilic arthropathy Microstructural cartilage changes are thought to precede macroscopic cartilage lesions 8 which are responsible for most of the morbidity of hemophilic arthropathy Conventional imaging techniques are unable to visualize early soft tissue and cartilage changes Evaluation of soft tissue changes and microstructural cartilage changes with sensitive imaging tools may direct clinical management and prophylaxis towards avoiding further irreversible macroscopic osteochondral damage New functional MRI techniques and 3DUS anatomic imaging may be able to diagnose early joint changes at a time where treatment is still effective to avoid further degeneration of the joint No prior studies have investigated the imaging of very early structural and physiologic events in hemophilic joints We will pioneer the development of novel imaging techniques for assessment of early soft tissue and cartilage changes in hemophiliacs Oral administration of FVIII DNA to modulate inhibitors in hemophilia mice Dr Gonzalo Hortelano McMaster University Hamilton Ontario First year funding The delivery of genes as therapeutic drugs is still facing numerous challenges particularly how to effectively deliver a therapeutic gene to the desired target cells and the immune responses generated by the immune system to foreign DNA and to foreign or new proteins Viruses are the most popular vehicle to deliver therapeutic genes since they are very efficient at infecting cells However some human trials have revealed some safety concerns that need to be addressed Additional and novel ways to deliver therapeutic genes would be desirable Ingestion of therapeutic genes would allow the intestine to produce a therapeutic protein for distribution throughout the body

    Original URL path: http://www.hemophilia.ca/en/research/chs-dream-of-a-cure-research-program/chs-research-grants-for-2012/ (2014-10-09)
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  • CHS Research Grants for 2011 - Canadian Hemophilia Society
    Safe Secure Blood Supply Products in the pipeline CHS Policy on Paid Plasma Donations Report Cards on Canada s Blood System 2008 2010 Report Card on Canada s Blood System 2005 2007 Report Card on Canada s Blood System 2003 2004 Report Card on Canada s Blood System 2002 Report Card on Canada s Blood System 1999 Report Card on Canada s Blood System Inhibitor rates related to treatment product in previously untreated patients Statement from the WFH variant Creutzfeldt Jakob disease vCJD CHS position on donor deferrals CHS position on HIV O deferral in Africa Hemophilia Research Million Dollar Club Research CHS Dream of a Cure Research Program General Criteria General Conditions Application Forms Summer Studentships in Inherited Bleeding Disorders Research CHS Research Grants for 2014 CHS Research Grants for 2013 CHS Research Grants for 2012 CHS Research Grants for 2011 CHS Research Grants for 2010 CHS Research Grants for 2009 CHS Research Grants for 2008 CHS Research Grants for 2007 CHS Research Grants for 2006 CHS Research Grants for 2005 The CHS Pfizer Care Until Cure Research Program General Criteria General Conditions Application Form Research Projects Funded in 2014 Research Projects Funded in 2013 Research Projects Funded in 2012 Research Projects Funded in 2011 Research Projects Funded in 2010 Research Projects Funded in 2009 Research Projects Funded in 2008 Research Projects Funded in 2007 Research Projects Funded in 2006 Research Projects Funded in 2005 CHS Novo Nordisk Psychosocial Research Program General Criteria General Conditions Application form Research Project Funded in 2014 Hemostasis Fellowship Program General Criteria General Conditions Application form Research Project Funded in 2014 Research Project Funded in 2013 Research Project Funded in 2012 Research Project Funded in 2011 Research Project Funded in 2010 Research Project Funded in 2009 Research Project Funded in 2008 Research Project Funded in 2007 Research Project Funded in 2006 Research Project Funded in 2005 CHS Baxter Fellowship Program General Criteria General Conditions Application Form Research Projects Funded in 2014 Research Project Funded in 2013 Opportunities to participate in research Opportunities to participate in marketing research studies International Development Karttik Shah Youth Fellowship International Twinning Projects Canadian Centre Twins Hemophilia Treatment Centre partnerships ended recently Canadian Hemophilia Society International Projects Fund Canadian Organizational Twins Recently closed twinning partnerships Treatment Centres British Columbia Alberta Saskatchewan Manitoba Ontario Quebec New Brunswick Prince Edward Island Nova Scotia Newfoundland and Labrador HCV HIV Hepatitis C and HIV Compensation I am a survivor HCV treatment support for 1986 1990 claimants National Endowment Fund Scholarship University of Ottawa Criminalization of HIV Non Disclosure HIV Know your rights US travel ban lifted World Hepatitis Day Recommendations for a Canadian Hepatitis C Strategy 2005 Hepatitis C An information booklet Alternative therapies Diagnosis Final Thoughts Getting treatment Healthy Lifestyle Hepatitis C Introduction Hepatitis C and HIV Co infection Psychosocial Aspects Standards of Care Symptoms Treatment Options for Hepatitis C Liver transplantation Youth Web About Us News Feed To Contact Us Commemoration of the Tainted Blood Tragedy Tree of Life Commemorations Canadian Blood

    Original URL path: http://www.hemophilia.ca/en/research/chs-dream-of-a-cure-research-program/chs-research-grants-for-2011/ (2014-10-09)
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  • CHS Research Grants for 2010 - Canadian Hemophilia Society
    Provincial Support Programs Insurance coverage Educational Material Printed documents Bleeding disorders in women Carriers of hemophilia A or B Hemophilia Hepatitis C HIV Inhibitors Physical activity and sports Platelet function disorders Rare factor deficiencies Relevant to all bleeding disorders Resources for children Von Willebrand disease Videos Care and Treatment Emergency Care Pain Management Nursing Physiotherapy Introduction Constitution of the Canadian Physiotherapists in Hemophilia Care CPHC Standards of Physiotherapy Care and Assessment Selected Journal Articles Educational material Bibliography Other resources Social Work Community Partners and Links Practice Guidelines Mission Services Interventions Standards of Practice Comprehensive Care Standards Safe Secure Blood Supply Products in the pipeline CHS Policy on Paid Plasma Donations Report Cards on Canada s Blood System 2008 2010 Report Card on Canada s Blood System 2005 2007 Report Card on Canada s Blood System 2003 2004 Report Card on Canada s Blood System 2002 Report Card on Canada s Blood System 1999 Report Card on Canada s Blood System Inhibitor rates related to treatment product in previously untreated patients Statement from the WFH variant Creutzfeldt Jakob disease vCJD CHS position on donor deferrals CHS position on HIV O deferral in Africa Hemophilia Research Million Dollar Club Research CHS Dream of a Cure Research Program General Criteria General Conditions Application Forms Summer Studentships in Inherited Bleeding Disorders Research CHS Research Grants for 2014 CHS Research Grants for 2013 CHS Research Grants for 2012 CHS Research Grants for 2011 CHS Research Grants for 2010 CHS Research Grants for 2009 CHS Research Grants for 2008 CHS Research Grants for 2007 CHS Research Grants for 2006 CHS Research Grants for 2005 The CHS Pfizer Care Until Cure Research Program General Criteria General Conditions Application Form Research Projects Funded in 2014 Research Projects Funded in 2013 Research Projects Funded in 2012 Research Projects Funded in 2011 Research Projects Funded in 2010 Research Projects Funded in 2009 Research Projects Funded in 2008 Research Projects Funded in 2007 Research Projects Funded in 2006 Research Projects Funded in 2005 CHS Novo Nordisk Psychosocial Research Program General Criteria General Conditions Application form Research Project Funded in 2014 Hemostasis Fellowship Program General Criteria General Conditions Application form Research Project Funded in 2014 Research Project Funded in 2013 Research Project Funded in 2012 Research Project Funded in 2011 Research Project Funded in 2010 Research Project Funded in 2009 Research Project Funded in 2008 Research Project Funded in 2007 Research Project Funded in 2006 Research Project Funded in 2005 CHS Baxter Fellowship Program General Criteria General Conditions Application Form Research Projects Funded in 2014 Research Project Funded in 2013 Opportunities to participate in research Opportunities to participate in marketing research studies International Development Karttik Shah Youth Fellowship International Twinning Projects Canadian Centre Twins Hemophilia Treatment Centre partnerships ended recently Canadian Hemophilia Society International Projects Fund Canadian Organizational Twins Recently closed twinning partnerships Treatment Centres British Columbia Alberta Saskatchewan Manitoba Ontario Quebec New Brunswick Prince Edward Island Nova Scotia Newfoundland and Labrador HCV HIV Hepatitis C and HIV Compensation I am a

    Original URL path: http://www.hemophilia.ca/en/research/chs-dream-of-a-cure-research-program/chs-research-grants-for-2010/ (2014-10-09)
    Open archived version from archive